| Player |
|
Status/Updated |
Notes |
| Tre Harris
|
WR |
Ques Sep. 5th - Undisclosed - 8/21/25 |
Harris is hampered by an undisclosed injury, and it is unknown if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Quentin Johnston
|
WR |
Ques Sep. 5th - Concussion - 8/17/25 |
Johnston is bothered by a concussion, and it is up in the air if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Trey Lance
|
QB |
Ques Sept 5 - Hand - 8/13/25 |
Lance is battling a hand injury, and it is uncertain if he will be active against the Chiefs on September 5th. |
| Branson Taylor
|
G |
Ques Sept. 5 - Knee - 8/12/25 |
Taylor is laid up with a knee injury, and it has yet to be determined if he will suit up for the opening clash against the Chiefs on Friday, September 5th. |
| Deane Leonard
|
DB |
Ques Sept. 5 - Leg - 8/11/25 |
Leonard is hampered by a leg injury, and it is up in the air if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Eric Rogers
|
CB |
Ques Sept 5 - Undisclosed - 8/11/25 |
Rogers is laid up with an undisclosed injury, and it is undetermined if he will participate against the Chiefs on September 5th. |
| Mekhi Becton
|
G |
Ques Sept. 5 - Undisclosed - 8/5/25 |
Becton is hampered by an undisclosed injury, and it is up in the air if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Otito Ogbonnia
|
DL |
Ques Sept. 5 - Undisclosed - 8/3/25 |
Ogbonnia is hampered by an undisclosed injury, and it is up in the air if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Ladd McConkey
|
WR |
Ques Sep. 5 - Undisclosed - 7/30/25 |
McConkey is tending to an undisclosed injury, and it is up in the air if he will be available for the September 5 game against the Kansas City Chiefs. |
| Jalen Reagor
|
WR |
Ques Sept 5 - Lower Body - 7/25/25 |
Reagor is battling a lower body injury, and it is unclear if he will dress against the Chiefs on September 5th. |
| Cam Hart
|
CB |
Ques Sept. 5 - Shoulder - 7/24/25 |
Hart is hampered by a shoulder injury, and it is up in the air if he will be active for the opening clash against the Chiefs on Friday, September 5th. |
| Ja'Sir Taylor
|
DB |
Ques Sept. 5 - Ribs - 7/24/25 |
Taylor is laid up with a rib injury, and it has yet to be determined if he will suit up for the opening clash against the Chiefs on Friday, September 5th. |
| Rashawn Slater
|
OT |
out for season - Knee - 8/10/25 |
Slater is placed on the injured reserve list due to a kneecap injury, and it is anticipated that he will miss the remainder of the season. |
| Savion Washington
|
OT |
Ques Sep. 5 - Undisclosed - 7/29/25 |
Washington has ended up on the PUP list with an undisclosed injury, and it is up in the air if he will take the field for the September 5 contest against the Kansas City Chiefs. |
| Najee Harris
|
RB |
Ques Sep. 5 - Eye - 7/29/25 |
Harris has popped up on the NFI list with an eye injury, and it is uncertain if he will be available for the September 5 game against the Kansas City Chiefs. |
| Del'Shawn Phillips
|
LB |
Out indefinitely - Undisclosed - 7/24/25 |
Phillips is placed on the PUP list with an undisclosed injury, and he is without a definitive timetable for return. |