| Player |
|
Status/Updated |
Notes |
| Mac Jones
|
QB |
Ques Sept. 7 - Knee - 8/20/25 |
Jones is hampered by a knee injury, and it remains to be seen if he will play on September 7 against the Seahawks. |
| Dominick Puni
|
OL |
Ques Sep. 7th - Knee - 8/17/25 |
Puni is battling an knee injury, and his availability for the September 7 matchup with the Seattle Seahawks is up in the air. |
| Nick Bosa
|
DL |
Ques Sep. 7th - Neck - 8/15/25 |
Bosa has injured his neck, and he is unlikely to be available for the September 7 contest against the Seahawks. |
| Jason Pinnock
|
S |
Ques Sep. 7th - Heel - 8/16/25 |
Pinnock has injured his heel, and it is unclear if he will be available for the September 7 game against the Seahawks. |
| C.J. West
|
DT |
Ques Sep. 7th - Knee - 8/14/25 |
West is nursing with a knee injury, and it is unclear if he will be active on September 7 against the Seahawks. |
| Jordan Watkins
|
WR |
Ques Sept. 7 - Ankle - 8/12/25 |
Watkins is nursing with an ankle injury, and it is unclear if he will be active on September 7 against the Seahawks. |
| Tatum Bethune
|
LB |
Ques Sept. 7 - Ankle - 8/11/25 |
Bethune is battling an ankle injury, and his availability for the September 7 matchup with the Seattle Seahawks is up in the air. |
| Marques Sigle
|
S |
Ques Sept 7 - Knee - 8/10/25 |
Sigle is dealing with a knee injury, and his availability for the September 7 matchup with the Seattle Seahawks is up in the air. |
| Upton Stout
|
CB |
Ques Sept 7 - Calf - 8/10/25 |
Stout is bothered by a calf injury, and it is unknown if he will be available against the Seattle Seahawks on September 7th. |
| Jordan Elliott
|
DL |
Ques Sept 7 - Back - 8/10/25 |
Elliott is nursing due to a back injury, leaving his status for the September 7 clash with the Seattle Seahawks up in the air. |
| Sam Okuayinonu
|
DL |
Ques Sep. 7 - Groin - 8/4/25 |
Okuayinonu is nursing with a groin injury, and it is unclear if he will be active on September 7 against the Seattle Seahawks. |
| Kyle Juszczyk
|
FB |
Ques Sep. 7 - Achilles - 8/4/25 |
Juszczyk is dealing with a achilles injury, and it is unknown if he will be available for the game against the Seattle Seahawks. |
| Jordan James
|
RB |
Ques Sept 7 - Knee - 8/16/25 |
James is hampered by a knee injury, and it remains to be seen if he will play on September 7 against the Seahawks. |
| Isaac Guerendo
|
RB |
Ques Sep. 7th - Shoulder - 8/2/25 |
Guerendo is nursing a shoulder injury, and it is unknown if he will be active against the Seahawks on September 7th. |
| Mykel Williams
|
DL |
Ques Sept. 7 - Ankle - 8/17/25 |
Williams is fighting off an knee injury, and it has yet to be determined if he will be active on September 7. |
| Jauan Jennings
|
WR |
Ques Sept 7 - Calf - 7/27/25 |
Jennings is nursing a calf injury, and it is unknown if he will be active against the Seahawks on September 7th. |
| Renardo Green
|
CB |
Ques Sept 7 - Hamstring - 7/26/25 |
Green is managing a hamstring injury, and it is unclear if he will if he will dress against the Seahawks on September 7th. |
| Ben Bartch
|
OL |
Ques Sep. 7th - Undisclosed - 8/13/25 |
Watkins is bothered by an undisclosed injury, and it is unclear if he will be active on September 7 against the Seahawks. |
| Alfred Collins
|
DL |
Ques Sep. 7 - Calf - 7/25/25 |
Collins is nursing a calf injury, and his availability for the September 7 contest against the Seattle Seahawks is uncertain. |
| Colton McKivitz
|
OL |
Ques Sep. 7 - Undisclosed - 7/25/25 |
McKivitz is bothered by an undisclosed injury, and it is unclear if he will suit up for the September 7 contest. |
| Darrell Luter Jr.
|
CB |
Ques Sep. 7 - Pelvis - 7/25/25 |
Luter Jr. is battling a pelvis injury, and his availability for the September 7 matchup with the Seattle Seahawks is up in the air. |
| Ji'ayir Brown
|
S |
Ques Sep. 7 - Ankle - 7/25/25 |
Brown is tending to an ankle injury, leaving his status for the September 7 clash with the Seattle Seahawks uncertain. |
| Robert Beal Jr.
|
DL |
Ques Sep. 7 - Ankle - 7/25/25 |
Beal Jr. is managing an ankle injury, and it is unknown if he will be available for the game against the Seattle Seahawks. |
| Deommodore Lenoir
|
DB |
Ques Sep. 7 - Shoulder - 7/25/25 |
Lenoir is fighting off a shoulder injury, and it has yet to be determined if he will be active on September 7. |
| Nick Martin
|
LB |
Out Sept. 7 - Lower Body - 8/12/25 |
Martin is hampered by a lower body injury, and he is unlikely to be available for the September 7 contest against the Seahawks. |
| Ameer Abdullah
|
RB |
out for season - Ribs - 8/27/25 |
Abdullah has been placed on the season ending injured reserve due to a ribs injury. |
| Bradlee Anae
|
DE |
out for season - Undisclosed - 8/27/25 |
Anae has been placed on the season ending injured reserve due to an undisclosed injury. |
| Equanimeous St. Brown
|
WR |
out for season - Foot - 8/27/25 |
St. Brown has been placed on the season ending injured reserve due to a foot injury. |
| Isaiah Prince
|
OT |
Out indefinitely - Knee - 8/26/25 |
Prince has hit the injured reserve list with a knee injury, and he will miss an extended period. |
| Jakob Robinson
|
CB |
out for season - Forearm - 8/28/25 |
Robinson is placed on the injured reserve list with a forearm injury, and he is projected to miss the remainder of the season. |
| Patrick Taylor Jr.
|
RB |
out for season - Shoulder - 8/20/25 |
Taylor Jr. has been added to the injured reserve list after he underwent season-ending surgery to repair a fracture in his shoulder, and has been shut down for the remainder of the season. |
| Tre Brown
|
CB |
out indefinitely - Heel - 8/22/25 |
Taylor has been added to the injured reserve list with a heel injury, and there is no timetable for his recovery. |
| Tarron Jackson
|
DL |
Out indefinitely - Undisclosed - 7/29/25 |
Jackson is dealing with an undisclosed injury, and it is unclear how long he will be idle. |
| Jacob Cowing
|
WR |
Out Indefinitely - Leg - 8/28/25 |
Cowing has been designated for the injured reserve list due to a leg injury, and he will miss an undetermined length of time. |
| Malik Mustapha
|
S |
Out indefinitely - Knee - 8/28/25 |
Mustapha has landed on the PUP list while recovering from a torn acl, and a timetable for return has yet to be established. |
| Ricky Pearsall
|
WR |
Ques Sep. 7 - Hamstring - 7/25/25 |
Pearsall has been shifted to the PUP list with a hamstring injury, leaving his status for the September 7 clash with the Seattle Seahawks up in the air. |
| Yetur Gross-Matos
|
DL |
Ques Sep. 7 - Undisclosed - 7/25/25 |
Gross-Matos has been assigned to the PUP list with an undisclosed injury, and it has yet to be determined if he will be in the lineup for the September 7 tilt. |
| Brandon Aiyuk
|
WR |
Out indefinitely - Knee - 8/28/25 |
Aiyuk is on the PUP list while recovering from knee surgery, and he will miss an extended period. |
| Kurtis Rourke
|
QB |
Out indefinitely - Knee - 8/28/25 |
Rourke has been shuttled to the NFI list with a knee injury, and he will miss an undetermined length of time. |
| Kevin Givens
|
DT |
Out indefinitely - Pectoral - 8/28/25 |
Givens is placed on the injured reserve list with a pectoral injury, and he will miss an extended period. |
| Trent Taylor
|
WR |
Out indefinitely - Undisclosed - 7/25/25 |
Taylor has been put on the injured reserve list with an undisclosed injury, and he is projected to miss the remainder of the season. |
| Tre Tomlinson
|
CB |
Out indefinitely - Undisclosed - 7/25/25 |
Tomlinson is on the injured reserve list due to an undisclosed injury, and is expected to be sidelined for the entire season. |